GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs10935120 | 1 | rs6802654 | chr3:134217072 | ANAPC13 | chr3:134196547-134204865:- | 0.39 | 12.57 | 1.72E-31 | Height |
| THCA | cis | rs10935120 | 1 | rs6802654 | chr3:134217072 | CEP63 | chr3:134204575-134293852:+ | 0.29 | 6.4 | 3.83E-10 | Height |
| THCA | cis | rs7374394 | 1 | rs6803443 | chr3:184940052 | CHRD | chr3:184097861-184107619:+ | 0.14 | 3.79 | 0.000168 | Cognitive performance |
| THCA | cis | rs9815354 | 1 | rs6803560 | chr3:41824480 | ULK4 | chr3:41288091-42003660:- | 1.07 | 19.88 | 1.58E-64 | Diastolic blood pressure |
| THCA | cis | rs9815354 | 1 | rs6803652 | chr3:41824556 | ULK4 | chr3:41288091-42003660:- | 1.07 | 19.88 | 1.58E-64 | Diastolic blood pressure |
| THCA | cis | rs9815925 | 1 | rs6804449 | chr3:184667576 | C3orf70 | chr3:184795840-184870802:- | -0.26 | -4.96 | 9.92E-7 | Heschl's gyrus morphology |
| THCA | cis | rs1552244 | 1 | rs6804473 | chr3:10060425 | C3orf10 | chr3:10157333-10168873:+ | -0.21 | -4.43 | 1.18E-5 | Alzheimer's disease |
| THCA | cis | rs1552244 | 1 | rs6804473 | chr3:10060425 | VHL | chr3:10183319-10193744:+ | -0.18 | -4.18 | 3.51E-5 | Alzheimer's disease |
| THCA | cis | rs1552244 | 1 | rs68045038 | chr3:10151828 | C3orf10 | chr3:10157333-10168873:+ | -0.21 | -4.51 | 8.24E-6 | Alzheimer's disease |
| THCA | cis | rs1552244 | 1 | rs68045038 | chr3:10151828 | VHL | chr3:10183319-10193744:+ | -0.19 | -4.44 | 1.13E-5 | Alzheimer's disease |
| THCA | cis | rs13191362 | 1 | rs68045643 | chr6:163029709 | PACRG | chr6:163148164-163736523:+ | 0.46 | 6.91 | 1.57E-11 | Body mass index |
| THCA | cis | rs3749237 | 1 | rs6804655 | chr3:49738945 | CCDC36 | chr3:49235861-49295537:+ | 0.18 | 3.78 | 0.000179 | Resting heart rate |
| THCA | cis | rs3749237 | 1 | rs6804655 | chr3:49738945 | RBM6 | chr3:49977592-50137484:+ | -0.14 | -4.19 | 3.28E-5 | Resting heart rate |
| THCA | cis | rs10935120 | 1 | rs6804770 | chr3:134230234 | ANAPC13 | chr3:134196547-134204865:- | 0.39 | 12.57 | 1.72E-31 | Height |
| THCA | cis | rs10935120 | 1 | rs6804770 | chr3:134230234 | CEP63 | chr3:134204575-134293852:+ | 0.29 | 6.4 | 3.83E-10 | Height |